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PSMC5 Rabbit mAb

     
  • WB - PSMC5 Rabbit mAb AP75971
    detail
  • IF - PSMC5 Rabbit mAb AP75971
    detail
  • IP - PSMC5 Rabbit mAb AP75971
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IP, ICC
Primary Accession P62195
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Monoclonal Antibody
Calculated MW 45626 Da
Additional Information
Gene ID 5705
Other Names PSMC5
Dilution WB~~1/500-1/1000
IP~~1/20
ICC~~N/A
Format Liquid
Protein Information
Name PSMC5
Synonyms SUG1
Function Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC5 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.
Cellular Location Cytoplasm. Nucleus.
Research Areas
Citations (0)
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$ 385.00
Cat# AP75971
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